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Table 1 Proteins identified by MALDI-TOF analysis

From: Recovery of brain biomarkers following peroxisome proliferator-activated receptor agonist neuroprotective treatment before ischemic stroke

Accession number Protein Function pI/MW (kDa) Peptides match/% Variation
P35213 14-3-3 isoform zeta, PKC inhibitor Signal transduction 5.5/28 9/40 ↑ I/R, ↑ Atorva
P35213 14-3-3 protein beta/alpha Signal transduction 4.8/28 7/31 ↑ Atorva, ↓ Feno
P45953 Acyl-CoA dehydrogenase, very long chain specific Lipid Metabolism, Mito 9.0/70.8 4/16 ↑ I/R
P84079 ADP rybosilation factor 1 Trafficking 6.3/20.7 4/16 ↑ I/R
Q9Z0U5 Aldehyde oxidase precursor Redox regulation 6.5/146.9 5/25 ↑↑ I/R, ↑I/R Atorva, ↑, I/R Feno
P37840 Alpha-synuclein Presynaptic/axon 4.7/14.5 4/11 ↓ I/R, ↓ Atorva
P23565 Alpha-internexin Intermediate filament 5.2/56.2 5/26 ↓ I/R
Q63754 Beta-synuclein Neuronal plasticity 4.5/14.3 5/17 ↑ I/R
Q05175 Brain acid soluble membrane protein (NAP 22) Growth cone/axon 4.5/21.8 4/15 ↑ I/R
O88767 DJ-1 Pleiotropic 6.3/20 5/31 ↓ I/R
P11598 Glucose related protein 58 kDa/PDIA3/Erp60 Thioredoxin/protein folding 5.9/57.6 4/17 ↑ I/R, ↓ Atorva
O35077 Glycerol-phosphate-deshydrogenase Metabolism 6.3/38 2/11 ↑ I/R
O35796 GCQ1QBP Glycoprotein Complement/Mito 4.8/30.7 4/21 ↓ I/R
P63039 HSP 60 Protein folding 8.2/58.08 5/14 ↑ I/R
Q07439 HSP 70.1/2 Protein folding 5.5/70.3 3/14 ↓ I/R
P34058 HSP 90 beta Protein folding 5.1/83.4 7/38 ↑ Feno
Q62689 Janus Kinase 2 Tyrosine kinase/inflammation 7.1/130.5 7/30 ↓ I/R, ↑ Atorva
P42123 Lactate dehydrogenase B chain Metabolism 5.7/36.6 6/25 ↓ I/R
P40925 Malate dehydrogenase Metabolism 6.2/36.7 3/15 ↑ I/R
Q62599 Metastasis associated protein 1 Unknown brain function 9.2/79.4 4/26 ↓ I/R
P52590 Nucleoporine 107 Nuclear pore 5.3/107.2 4/26 ↓ I/R
P35704 Peroxiredoxine 2 Redox regulation 5.3/21.8 6/42 ↑ Feno
P31044 Phosphatidylethanolamine-binding protein Serine protease inhibitor 5.5/20.8 6/17 ↓ I/R
P35291 Rab16 Trafficking 5.0/22 4/25 ↑ Atorva, ↑ Feno
P49803 Regulator of G protein signaling 7 Signal transduction 8.3/55.7 4/50 ↑ I/R
P11507 Serca 2 Calcium Homeostasis 5.2/114.7 12/14 ↓ I/R
P21707 Synaptotagmin I Synapse 8.8/47.8 4/22 ↑ I/R
P47942 TUC-4 / TOAD 64 (DYPL/CRMP) Axonal guidance/development 6.0/62.2 15/71 ↑ I/R